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Patients were divided into the following subgroups: (1) 7 patients with newly diagnosed CD (age range, 19-62 years

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The etiology of IR in CKD is multifactorial, depending on classical and CKD-peculiar risk factors, such as physical inactivity, inflammation and oxidative stress, adipokine derangements, vitamin D deficiency, metabolic acidosis, anemia and microbial toxins (Spoto et al., 2016)